Zocor Precautions and Warnings

Specific Zocor Precautions and Warnings

Some precautions and warnings to be aware of prior to taking Zocor include:


  • Studies have suggested that Chinese people may be at a higher risk for problems when Zocor is combined with niacin (see Niacin and Zocor for more information)


  • If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting Zocor. Alcohol can affect the way the liver works, indirectly affecting Zocor.
  • Statins have been known to cause an increase in liver enzymes. Therefore, it is recommended that you have a blood test that looks at your liver function before starting Zocor. These tests may also be recommended if the Zocor dosage is changed (see Zocor and Liver Problems).
Previously it had been recommended that people taking statins have routine periodic liver function tests while taking the medication, but this recommendation has been removed, since such monitoring does not help much to detect or prevent such problems. Liver function tests should still be performed if there is any suspicion of liver damage. 
  • Rhabdomyolysis (the severe breakdown of muscles) and other serious muscle problems have rarely been reported with Zocor and other statins. You are at greater risk for developing muscle problems, such as rhabdomyolysis, with this drug if you:
    • Take a higher Zocor dosage (such as 80 mg a day)
    • Have kidney damage
    • Are elderly
Make sure to contact your healthcare provider immediately if you experience any muscle pain, weakness, or tenderness, especially if it is accompanied by a fever or if you feel ill (see Zocor and Muscle Pain).
  • Zocor is a pregnancy Category X medicine, meaning that it could potentially cause harm to your unborn child. The safety of this drug in pregnant women has not been established. If you are pregnant, talk with your healthcare provider immediately (see Zocor and Pregnancy).
  • It is not known whether Zocor passes through breast milk. Ask your healthcare provider whether to stop nursing or stop taking Zocor.
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