Zocor Drug Interactions

If you are taking both Zocor and fibrates, your body may metabolize the medications differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis.

 

Both niacin and Zocor alone can increase the chances of developing serious muscle problems. Therefore, it is thought that combining these medicines may cause an even greater risk. If you are taking both Zocor and niacin, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments (see Niacin and Zocor).

 

There is a possibility that when Zocor is taken with antifungals, you are at higher risk of developing muscle problems. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.

 

If you are taking Zocor with erythromycin, clarithromycin, or telithromycin, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.

 

If you are taking Zocor and an HIV protease inhibitor, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.

 

Examples of HIV protease inhibitors include:

 

If you are taking Zocor and nefazodone, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.

  

Taking amiodarone and Zocor together may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Zocor dosage should not exceed 20 mg.