Zocor Drug Interactions (Cont.)

More Information on Interactions With Zocor

The following sections explain in detail the potentially negative interactions that can occur when Zocor is combined with any of the drugs listed above.
  
Cyclosporine
Taking both cyclosporine and Zocor together may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Zocor dosage should not exceed 10 mg.
 
Danazol
Taking danazol and Zocor together may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your dosage of Zocor should not exceed 10 mg.
 
Warfarin
If you are taking both Zocor and warfarin, your body may metabolize the medicines differently than intended. When starting Zocor therapy and/or changing the Zocor dosage, your healthcare provider may choose to monitor your INR and prothrombin time more closely and make any necessary adjustments. Prothrombin time and INR are tests used to measure how well your blood is clotting.
 
Gemfibrozil
If you are taking both Zocor and gemfibrozil, your body may metabolize the drugs differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis. To decrease this risk, your dosage of Zocor should not exceed 10 mg.
(Zocor Drug Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;