Zocor Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Zocor is combined with any of the drugs listed above.
Amlodipine
Combining
amlodipine with Zocor may increase the risk of serious muscle problems (such as myopathy or rhabdomyolysis). If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your dosage of Zocor should not exceed 20 mg.
Cyclosporine
Taking
cyclosporine and Zocor together is not recommended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis.
Danazol
Taking danazol and Zocor together is not recommended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis.
Diltiazem
Combining
diltiazem with Zocor may increase the risk of serious muscle problems (such as myopathy or rhabdomyolysis). If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your dosage of Zocor should not exceed 10 mg.
Warfarin
If you are taking both Zocor and
warfarin, your body may metabolize the medicines differently than intended. When starting Zocor therapy and/or changing the
Zocor dosage, your healthcare provider may choose to monitor your
INR and prothrombin time more closely and make any necessary adjustments. Prothrombin time and INR are tests used to measure how well your blood is clotting.
Gemfibrozil
Taking
gemfibrozil and Zocor together is not recommended. This can cause significant reactions, including increasing the risk of developing serious muscle problems like myopathy or rhabdomyolysis.
Niacin
Both
niacin and Zocor alone can increase the chances of developing serious muscle problems. Therefore, it is thought that combining these medicines may cause an even greater risk. If you are taking both Zocor and niacin, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments
(see Niacin and Zocor). This is particularly important for people of Chinese descent, as studies have suggested that Chinese people may be at a higher risk for problems when combining niacin and Zocor.