For most people with high cholesterol, the recommended starting dosage of Zocor is 20 mg to 40 mg once daily, taken at night. The average daily dose is 5 mg to 80 mg once daily. Children ages 10 to 17 are recommended to take a starting dose of 10 mg once daily. A few factors that can affect dosing include your age and cholesterol goal, as well as other medical conditions you may have.
The dosage of Zocor® (simvastatin) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your age
- The medical condition you are being treated for
- Other medical conditions you may have
- Other medications you may be currently taking
- Your cholesterol goal.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
The recommended starting dose of Zocor for most people with high cholesterol is Zocor 20 mg to 40 mg once a day, taken at night. If you are over 65 years of age, have severe kidney disease, or are taking certain other medications, your healthcare provider may choose to start you on a lower dosage (and may suggest a lower maximum dosage as well). Some of the medications that interact with Zocor in such a way as to require lower-than-usual Zocor dosages include:
- Amiodarone (Cordarone®, Pacerone®)
- Amlodipine (Norvasc®)
- Diltiazem (Cardizem®, Cardizem CD®, Cardizem LA®, Cartia XT®, Dilacor XR®, Dilt-CD®, Diltia XT®, Dilt-XR®, Taztia XT®, Tiazac®)
- Lomitapide (Juxtapid®)
- Ranolazine (Ranexa®)
- Verapamil (Calan®, Calan SR®, Covera-HS®, Isoptin SR®, Verelan®, Verelan PM®).
(Click Zocor Drug Interactions for more information.)
After several weeks, your healthcare provider will recommend that you return to have your cholesterol levels checked again. If you have not reached your cholesterol goal at this time, your healthcare provider may choose to increase your Zocor dosage. The dosage can also be decreased if side effects occur.
Due to the increased risk of serious muscle problems at higher dosages, the maximum recommended Zocor dosage is 40 mg per day. However, people who have already been taking 80 mg daily for a year or more with no muscle problems may continue to take that dosage.