Zocor and Memory Loss

Memory loss is a rare Zocor side effect, occurring in less than 1 percent of people who take the drug. Because of its infrequency and the conflicting research on Zocor and memory loss, it is difficult to say whether the memory loss is caused by Zocor or something else. If you do experience memory loss while taking Zocor, contact your healthcare provider. He or she may recommend adjusting your Zocor dosage or switching to a different cholesterol drug.

 

Zocor and Memory Loss: An Overview

While most people tolerate Zocor® (simvastatin) well, there are possible side effects that can occur. Memory loss (known medically as amnesia) is a rare side effect that occurs in less than 1 percent of people who take Zocor. Because memory loss with Zocor occurs so infrequently, it is difficult to know whether the memory loss is because of Zocor or something else.
 

Zocor and Memory Loss: What Does the Research Say?

Little research has been done on the effects of Zocor on memory loss and other brain conditions, such as dementia. Furthermore, the research that has been done is conflicting. For example, some studies have shown that people taking Zocor have a lower chance of developing dementia. Other studies have shown no benefit.
 
In medical journals, there have been a number of isolated reports of memory loss in people taking Zocor. However, this number is small compared to the number of people taking Zocor. Therefore, it is difficult to say whether the memory loss is triggered by Zocor or something else.
 

Zocor and Memory Loss: Summary

For people on Zocor, memory loss appears to happen infrequently.
 Make sure to talk with your healthcare provider or pharmacist if you have concerns about Zocor and memory loss. Also, keep in mind that it is not possible for your healthcare provider to know whether you will have a side effect with a medicine that you have never taken. Therefore, if you notice any memory loss while taking Zocor, talk to your healthcare provider. He or she may recommend adjusting the Zocor dosage or switching to another cholesterol medication.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;