For people taking Zocor, joint pain is possible. Make sure to talk with your healthcare provider or pharmacist if you have concerns about Zocor and joint pain. Also, keep in mind that it is not possible for your healthcare provider to know whether you will have a side effect with a medicine that you have never taken. Therefore, if you notice any joint pain while taking Zocor, notify your healthcare provider. If the joint pain continues after the first couple of months, your doctor may recommend adjusting your Zocor dosage or switching to another cholesterol medication.