Zetia Drug Interactions

Zetia drug interactions can change how your body metabolizes the drugs, affect Zetia's ability to lower cholesterol, and increase the risk of developing myopathy (a potentially serious muscle condition), among other things. Some of the drugs that can potentially interact with Zetia include cyclosporine, cholestyramine, fenofibrate, and other fibrates (including gemfibrozil). Be sure to talk with your healthcare provider about specific drug interactions with Zetia that may apply to you.

 

Zetia Drug Interactions: An Introduction

Zetia® (ezetimibe) can potentially interact with a number of other medicines. Some possible Zetia drug interactions can include:
 

 

More Detail About Zetia Interactions

 
Fenofibrate (Antara, Tricor, Lipofen, Triglide, Lofibra)
Zetia is often prescribed with fenofibrate because when combined, these medications are effective at lowering total
 cholesterol, LDL cholesterol, and triglycerides -- as well as raising HDL cholesterol. However, taking both fenofibrate and Zetia together may increase the levels of Zetia in the blood. This can cause problems in people with gallbladder disease. In these cases, other cholesterol-lowering medicine may be recommended.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;