WelChol Drug Interactions

There are several potential WelChol drug interactions to be aware of. For example, if you are taking WelChol at the same time as you are taking certain other drugs, such as oral contraceptives, warfarin, or vitamin K products, WelChol can decrease the absorption of these drugs into the body and thereby lower their effectiveness. You may need to separate doses by four hours to avoid WelChol drug interactions.

 

WelChol Drug Interactions: An Overview

WelChol® (colesevelam hydrochloride) has the potential to interact with a number of other medications. Medicines that can cause WelChol drug interactions include:
 
These are just the known interactions with WelChol. Because WelChol has the potential to bind with and decrease the absorption of many drugs, talk with your healthcare provider about specific interactions that may be important in your situation. It is a good idea to take any medication that is important (such as an arrhythmia medication) at least four hours before a dose of WelChol.
 

WelChol Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when WelChol is combined with any of the drugs listed above.
 
 
Certain Vitamins
WelChol may decrease the absorption of fat-soluble vitamins, such as vitamin A, vitamin D, vitamin E, or vitamin K. You should take any such vitamins at least four hours before a dose of WelChol.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;