Vytorin Side Effects
Common side effects of Vytorin include upper respiratory infections, weakness, and increased liver enzymes. While most side effects are minor, if you experience unexplained muscle pain, tenderness, or weakness with a fever, contact your healthcare provider immediately -- it could be a sign of a serious problem. Other potential side effects that may require attention include trouble breathing, passing dark-colored urine, and unexplained rash.
As with any medicine, side effects are possible with Vytorin® (ezetimibe/simvastatin), but not everyone who takes the drug will develop side effects. In fact, most people tolerate it quite well. If side effects do occur, they are generally minor and either require no treatment or can easily be treated by you or your healthcare provider.
If you are taking Vytorin and experience unexplained muscle pain, tenderness, or weakness (especially if accompanied by a fever or feeling of illness), it is important to contact your healthcare provider right away.
(This article discusses many, but not all, side effects seen with Vytorin. Your healthcare provider can discuss a more complete list of Vytorin side effects with you.)
Vytorin has been studied extensively in clinical trials, with more than 3,800 people having been evaluated. In these studies, side effects are always documented and compared to side effects that occurred in a similar group of people taking a placebo (a "sugar pill" with no active ingredients). This way, it is possible to see what side effects occurred, how often they occurred, and how they compared to the group not taking the medicine. Based on these studies, the most common Vytorin side effects included:
- Headache -- in up to 5.8 percent of people
- Diarrhea -- up to 5 percent
- Upper respiratory infection, such as the common cold -- up to 5 percent of people
- Muscle pain, known medically as myalgia -- up to 3.6 percent of people (see Vytorin and Muscle Pain)
- Flu -- up to 2.3 percent of people
- Pain, including back pain -- up to 2.3 percent of people
- Pain in an extremity (arm or leg) -- up to 2.3 percent.
- General feeling of weakness (asthenia)
- Indigestion (dyspepsia)
- Unexplained rash
- Abdominal pain (stomach pain)
- Urinary tract infection (UTI)
- A spinning sensation (vertigo)
- Sinus infection or inflammation
- Joint pain (see Vytorin and Joint Pain).