Vytorin Drug Interactions

Niacin
Both niacin and Vytorin alone can increase the chances of developing serious muscle problems. Therefore, combining these medicines may cause an even greater risk. If you are taking both of these products, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments (see Niacin and Vytorin).
 
This is particularly important for people of Chinese descent, as studies have suggested that Chinese people may be at a higher risk for problems when combining niacin and simvastatin (one of the components of Vytorin).
 
Protease Inhibitors
Vytorin and an HIV protease inhibitor should not be combined. This can cause significant reactions, including increasing the risk of developing serious muscle problems, such as myopathy or rhabdomyolysis.
 
Nefazodone
Taking Vytorin with nefazodone is not recommended, as your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems, such as myopathy or rhabdomyolysis.
 
Ranolazine
Combining ranolazine with Vytorin may increase the risk of serious muscle problems (such as myopathy or rhabdomyolysis). If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your dosage of Vytorin should not exceed 10/20 mg daily.
  
Verapamil
Combining verapamil and Vytorin may cause your body to metabolize the drugs differently than intended. This can cause significant reactions, including increasing the risk of developing serious muscle problems (myopathy or rhabdomyolysis). If you are taking both of these medicines, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Vytorin dosage should not exceed 10/10 mg.
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Vytorin Information

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