Niacin
Both
niacin and
Vytorin alone can increase the chances for developing serious muscle problems. Therefore, it is thought that when combined, these medicines may cause an even greater risk. If you are taking both Vytorin and niacin, your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments
(see Niacin and Vytorin).
Antifungals
There is a possibility that when Vytorin is taken in conjunction with these medications, you are at higher risk of developing muscle problems. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.
Erythromycin, Clarithromycin, or Telithromycin
If you are taking Vytorin with erythromycin,
clarithromycin, or telithromycin, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken simultaneously.
HIV Protease Inhibitors
If you are taking Vytorin with an
HIV protease inhibitor, your body may metabolize the drugs differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.
Examples of HIV protease inhibitors include:
Nefazodone
If you are taking both Vytorin and
nefazodone, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.
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