Vytorin Drug Interactions

Combining danazol and Vytorin may increase the level of Vytorin in your blood. This can cause significant reactions, including increasing the risk of developing serious muscle problems, such as myopathy or rhabdomyolysis. If you are taking these medicines together, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Vytorin dosage should not exceed 10/10 mg, and you should not start taking Vytorin unless you have already been able to tolerate simvastatin (Zocor) at a dose of 5 mg or higher.

 

Taking digoxin and Vytorin together appears to slightly increase the levels of digoxin in the blood. When starting Vytorin or increasing the dosage, your healthcare provider may choose to monitor you more closely.

 

If you are taking Vytorin and a fibrate, you may have an increased risk for serious reactions, including serious muscle problems. Gallbladder problems could also occur. At this time, people are advised against combining a fibrate with Vytorin.

 

People on Vytorin should not consume grapefruit juice, grapefruit, or grapefruit supplements because doing so can increase the levels of Vytorin in the blood. This can increase the chances of developing a serious muscle problem (for example, myopathy or rhabdomyolysis), which can cause the kidneys to stop working (see Vytorin and Muscle Pain).

 

If you are currently taking Vytorin, do not increase or decrease your grapefruit consumption without consulting with your healthcare provider (see Grapefruit Juice and Vytorin for more information).