Vytorin Drug Interactions

Taking amiodarone and Vytorin together may increase the risk of developing serious muscle problems, such as myopathy or rhabdomyolysis. If you are taking both of these medicines, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Vytorin dosage should not exceed 10/20 mg once daily.

 

Bile acid sequestrants can bind to Vytorin in the digestive tract, preventing it from being absorbed into the bloodstream. To avoid this drug interaction, be sure to take Vytorin at least two hours before or four hours after a bile acid sequestrant.

 

Some antifungals and antibiotics can significantly increase the level of Vytorin in your blood, possibly increasing your risk for side effects, including the risk of developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together. Your healthcare provider may recommend that you stop taking Vytorin temporarily while your bacterial or fungal infection is treated.

 

Taking cyclosporine and Vytorin together may increase the level of Vytorin in your blood. This can cause significant reactions, including increasing the risk of developing serious muscle problems, such as myopathy or rhabdomyolysis. If you are taking both of these medicines, your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Vytorin dosage should not exceed 10/10 mg, and you should not start taking Vytorin unless you have already been able to tolerate simvastatin (Zocor^®) at a dose of 5 mg or higher.