Vytorin and Memory Loss

Although side effects may occur with Vytorin, and memory loss is a recognized problem, it is uncommon in people taking the drug. As a result, it is difficult to determine whether the memory loss is actually caused by the medication or by another factor. If you are taking Vytorin and memory loss becomes a problem, notify your healthcare provider. He or she may change your dosage or recommend a different drug.

 

Vytorin and Memory Loss: An Overview

While most people tolerate Vytorin® (ezetimibe/simvastatin) well, there are potential side effects that can occur. For people taking Vytorin, memory loss (known medically as amnesia) is a rare but possible side effect, occurring in less than 1 percent of people. Because memory loss with Vytorin occurs so infrequently, it is difficult to know whether the memory loss is actually caused by Vytorin or by something else.
 

Vytorin and Memory Loss: What Does the Research Say?

Little research has been conducted on Vytorin (or on statins and cholesterol absorption inhibitors in general) and its effect on memory loss and other brain conditions. Furthermore, the research that has been done is conflicting. For example, some studies have shown that people taking statins have a lower chance of developing dementia. Other studies have shown no benefit.
 
In medical journals, there have been a number of isolated reports of memory loss in people taking statins. However, this number is small compared to the number of people taking statins. Therefore, again, it is difficult to say whether the memory loss is because of statins, such as Vytorin, or actually caused by something else.
 

Vytorin and Memory Loss: A Summary

For people on Vytorin, memory loss appears to happen infrequently.
 However, talk with your healthcare provider or pharmacist if you have concerns about Vytorin and memory loss. Also, keep in mind that it is not possible for your healthcare provider to know beforehand whether you will have a side effect with a medicine that you have never taken before. If you notice any memory loss while taking Vytorin, talk to your healthcare provider. He or she may recommend adjusting the Vytorin dosage or switching to another cholesterol medication.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;