Trilipix is approved for the treatment of unhealthy triglyceride and cholesterol levels. Specifically, it is used to increase HDL cholesterol and reduce triglycerides and both total and LDL cholesterol. Healthcare providers may also occasionally recommend off-label uses for Trilipix, such as preventing heart attacks, strokes, or cardiovascular disease.
Trilipix™ (fenofibric acid delayed-release, also known as choline fenofibrate) is a prescription medication licensed to treat unhealthy triglyceride and cholesterol levels. It is approved for use by itself or in combination with a statin, another type of cholesterol medication. Specifically, Trilipix is approved for the following uses:
- Improving cholesterol and triglyceride levels in people with hypercholesterolemia (high cholesterol) or dyslipidemia (unhealthy cholesterol and/or triglyceride levels). Trilipix can reduce both total and LDL cholesterol (bad cholesterol) and raise HDL cholesterol (good cholesterol), while decreasing triglycerides.
- Increasing HDL cholesterol and decreasing triglycerides in people already being optimally treated with a statin medication to reach their LDL goal. This use is approved only for people with coronary heart disease (CHD) or certain other risk factors, such as diabetes, peripheral artery disease, carotid artery disease, or an aortic aneurysm.
- Lowering triglyceride levels in people with hypertriglyceridemia (high triglycerides). Triglycerides are fat-like substances found in the body.
High levels of cholesterol in the blood can accumulate on the walls of arteries (known as atherosclerosis or hardening of the arteries), leading to decreased blood flow and oxygen supply to the heart, brain, and other areas of the body. This can greatly increase a person's risk for developing conditions such as heart disease, angina (chest pain), heart attack, and stroke.
Trilipix has been licensed for the treatment of high cholesterol in addition to a low-cholesterol diet and exercise. It works by lowering total cholesterol, LDL cholesterol, triglycerides, and Apo B (a component of cholesterol that is related to several heart disease risk factors). It can also raise HDL cholesterol, which is the good cholesterol.
In general, cholesterol treatment is aimed at lowering LDL cholesterol levels enough to reduce the risk of developing complications associated with high cholesterol (see Effects of High Cholesterol). If you are at a higher risk, you will have a lower LDL goal.
(Click High Cholesterol Risk to see a list of risk factors that may affect your cholesterol level and a general guideline of ideal LDL cholesterol levels.)