Why Take Statins in the Evening?

Many statins (but not all) must be taken in the evening. The liver produces the most cholesterol in the middle of the night (in the early morning hours). Therefore, it is best to take the short-acting statins in the evening -- taking them early in the day would decrease their effectiveness. This advice applies to the following medications:
Longer-acting statins can be taken at any time of the day, although you should take them consistently at the same time each day. These longer-acting medications include:

Dosing Information

The dose of a statin that your healthcare provider recommends will vary, depending on a number of factors, including:
  • The particular statin product
  • How you respond to the medication
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(For more information, see your particular statin drug within
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Statin Medication Information