How Do Statin Drugs Work?
Statins work by inhibiting a particular enzyme, HMG-CoA reductase, which controls the rate of
cholesterol production in the body. This causes the liver to make less cholesterol. Statin drugs also:
- Increase the liver's ability to collect and get rid of LDL cholesterol ("bad" cholesterol)
- Increase HDL cholesterol ("good" cholesterol)
- Decrease triglycerides.
What Should I Tell My Healthcare Provider?
You should talk with your healthcare provider prior to taking a statin if you have:
- Liver disease, such as cirrhosis, liver failure, or hepatitis
- Kidney disease, such as kidney failure (renal failure)
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
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