Statin Drugs -- What You Should Know

How Do Statin Drugs Work?

Statins work by inhibiting a particular enzyme, HMG-CoA reductase, which controls the rate of cholesterol production in the body. This causes the liver to make less cholesterol. Statin drugs also:
 
  • Increase the liver's ability to collect and get rid of LDL cholesterol ("bad" cholesterol)
  • Increase HDL cholesterol ("good" cholesterol)
  • Decrease triglycerides.
     

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking a statin if you have:
 
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Statin Warnings and Precautions to learn more, including information on who should not take the drug.)
 
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