Statin Drug Simcor

Simcor® (niacin extended-release/simvastatin) is a prescription medication that contains two different cholesterol-lowering drugs: extended-release niacin (or nicotinic acid) and simvastatin (a statin).
As a statin drug, Simcor works by blocking a particular enzyme (HMG-CoA reductase) that controls the rate of cholesterol production in the body. This causes the liver to make less cholesterol. It also increases the liver's ability to collect and get rid of LDL cholesterol.
It is not completely understood how the other component of Simcor works. It is thought that niacin works to increase HDL cholesterol ("good" cholesterol) levels by preventing the liver from removing HDL from the bloodstream. Additionally, niacin seems to decrease the liver's production of LDL and VLDL, two types of "bad" cholesterol. Niacin also helps decrease the release of fatty acids (from body fat) into the bloodstream.
(Click Simcor for more information about this drug, including information about its effects, dosing guidelines, and potential side effects.)
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