The medication comes in tablet form and is available by prescription only. Simcor tablets are generally taken once a day, at bedtime with a low-fat snack. Alcohol and hot drinks may worsen flushing symptoms and itchy skin (common side effects of Simcor); these drinks should be avoided close to the time that the medicine is taken. It is also recommended that people who are on Simcor avoid drinking large quantities of grapefruit juice because it can increase the levels of simvastatin in the blood.
In one clinical study, people taking Simcor 1000/20 mg once daily were able to, on average, decrease
LDL ("bad" cholesterol) by 11.9 percent, decrease triglycerides by 26.5 percent, and
increase HDL ("good" cholesterol) by 20.7 percent. Generally, the effects of Simcor on cholesterol and triglyceride levels were greater with higher doses of the medication.
(Click Simcor to find out how this medication works to lower triglyceride and cholesterol levels, for more information on when and how to take Simcor tablets, and to learn about the potential side effects of this drug.)
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