Simcor Drug Interactions

Cyclosporine
Taking both cyclosporine and Simcor together may increase the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments.
 
Fibrates
Combining a fibrate with Simcor increases the risk of serious muscle problems. This combination should be avoided unless the potential benefits outweigh the risks of the drug interaction.
 
Danazol
Taking both danazol and Simcor together may increase the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments.
 
Digoxin
Simcor may slightly increase the level of digoxin in the blood. Your healthcare provider may want to monitor your digoxin levels when you start or stop taking Simcor (or even when changing your Simcor dosage).
 
Grapefruit
It is recommended that people on Simcor avoid drinking large quantities of grapefruit juice, eating grapefruit, or using grapefruit supplements because it can increase the levels of Simcor in the blood. This can increase the chances for developing a serious muscle problem (myopathy or rhabdomyolysis), which can cause the kidneys to stop working.
 
If you are being treated with Simcor and want to continue drinking grapefruit juice, talk to your healthcare provider about other cholesterol medications that you can take (see Simcor and Grapefruit for more information).
 
Nefazodone
Combining nefazodone with Simcor increases the risk of serious muscle problems. In general, these medications should not be taken together.
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Simcor Medication Information

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