Simcor Drug Interactions

More Details About Simcor Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when Simcor is combined with any of the drugs listed above.

 

Taking both amiodarone and Simcor increases the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments.

 

Bile acid sequestrants bind to niacin (one of the active ingredients of Simcor) in the digestive tract, preventing it from being absorbed into the bloodstream. This makes Simcor much less effective. Be sure to separate Simcor and a bile acid sequestrant by as much time as possible, at least four to six hours.

 

Combining Simcor with a high blood pressure medication may increase the risk of low blood pressure (hypotension). Be sure to let your healthcare provider know if you develop any signs of this problem, such as lightheadedness, dizziness, or fainting. Check with your healthcare provider before combining Simcor with a blood pressure medication.

 

Some antibiotics may increase the level of Simcor in your blood, increasing the risk of Simcor side effects, including dangerous side effects such as myopathy or rhabdomyolysis. These medications should not be taken together with Simcor; instead, alternative antibiotics should be recommended. If no suitable alternatives are available, you should stop taking Simcor while taking the antibiotic.

 

Some antifungal medications may increase the level of Simcor in your blood, increasing the risk of Simcor side effects, including dangerous side effects such as myopathy or rhabdomyolysis. These medications should not be taken together with Simcor; instead, alternative antifungals should be recommended. If no suitable alternatives are available, you should stop taking Simcor while taking the antifungal.