Red Yeast Rice Drug Interactions

Nefazodone (Serzone)
Taking nefazodone and red yeast rice simultaneously may increase your risk of side effects due to the lovastatin component of red yeast rice. If you take nefazodone, do not take red yeast rice without your healthcare provider's knowledge and supervision.
 
Niacin (Nicotinic Acid, Niacor, Nicolar)
Combining niacin with red yeast rice may increase the risk of serious muscle problems due to the lovastatin content of red yeast rice. Talk with your healthcare provider before taking red yeast rice with niacin, including non-prescription niacin supplements.
 
Statins
Red yeast rice contains a statin medication. Therefore, combining it with other statin medications may increase the risk of serious muscle problems, such as myopathy or rhabdomyolysis. In general, you should not use more than one statin at the same time.
 
Protease Inhibitors
Taking red yeast rice with a protease inhibitor may increase the level of the lovastatin component of red yeast rice in your blood. This can increase your risk of side effects, including serious muscle problems. If you take a protease inhibitor, do not take red yeast rice without your healthcare provider's approval.
 
Sildenafil (Viagra, Revatio)
Sildenafil may increase the level of lovastatin in your blood, potentially increasing your risk of serious side effects. Do not take red yeast rice with sildenafil without first talking to your healthcare provider.
 

Final Thoughts on Red Yeast Rice Drug Interactions

It is possible that not every drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the red yeast rice drug interactions that may apply to you.
 
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