Because policosanol is not a medication and is not closely regulated, no standard policosanol dosage has been established. However, some dosing guidelines can be obtained from clinical studies and practical experience with the supplement. Some studies used policosanol doses of 5 mg to 10 mg twice daily for treating high cholesterol and 10 mg twice a day for treating intermittent claudication.
An Introduction to Policosanol DosageThe recommended dose of policosanol has not been clearly established. Unlike medications, for which the standard doses have been well established in carefully designed studies, there is less information available for determining the best dose for most herbal supplements, including policosanol.
Is There a Reasonable Policosanol Dose?With prescription and non-prescription medications, researchers establish the most effective and safest doses during special studies, known as dose-range studies. These studies are done early in the development of medications, long before they are ever approved. However, because herbal supplements do not require approval from the U.S. Food and Drug Administration (FDA), dose-range studies are rarely performed. Without such studies, only vague "trial and error" information is available.
Some information about policosanol dosing can be obtained from clinical studies and from practical experience with the supplement. For treating high cholesterol, doses of 5 mg to 10 mg twice daily have been used, although some studies have used doses as high as 80 mg a day. For treating intermittent claudication, policosanol doses of 10 mg twice a day have been used in some studies.
General Information on Dosing With PolicosanolConsiderations for people taking policosanol include the following:
- Because the manufacturing of supplements such as policosanol is not closely regulated, it is important to choose a trustworthy manufacturer for your supplements. Your pharmacist is a good source of information regarding which manufacturers are more reputable than others.
- It is not known if policosanol products that are manufactured in the United States are equivalent to Cuban-produced policosanol, which was used in most of the clinical studies.
- If you have any chronic health problems or take any prescription medications, you should check with your healthcare provider before taking policosanol.
- If you are unsure about anything related to your dosage or policosanol dosing in general, please talk with your healthcare provider.