Niacin Drug Interactions

Diabetes Medications
Niacin can increase blood sugar, especially at high doses (like the niacin dosage used to improve cholesterol). Sometimes, this increase in blood sugar gets better once a stable niacin dose is reached, although this is not always the case. You may need to monitor your blood sugar more often, especially while starting or stopping niacin, and your healthcare provider may need to adjust the dose of your diabetes medications.
 
Gout Medications
Gout can increase uric acid levels in the blood, increasing the risk of gout attacks. Your healthcare provider may need to increase the dose of your gout medication.
 
Nitrates
Combining niacin with a nitrate could lead to an unsafe drop in blood pressure. Check with your healthcare provider before combining niacin with a nitrate.
 
Statins
Rarely, rhabdomyolysis (a dangerous muscle problem) has been reported in people who took a statin medication with niacin. It is not clear if niacin (or just the statin) contributed to such problems. Statins are often combined with niacin for their complementary benefits for cholesterol. If you take such medications together, be sure to watch for any signs of rhabdomyolysis, such as unexplained muscle pain or weakness.
 
Warfarin
Niacin may affect blood platelets and blood clotting times. Therefore, check with your healthcare provider before taking niacin with warfarin. You may need to be monitored more closely, especially when starting or stopping niacin.
 

Final Thoughts on Niacin Drug Interactions

It is possible that not all niacin drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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