Treating high cholesterol and a rare genetic condition called sitosterolemia are among the licensed uses of Zetia. The cholesterol medication is effective at decreasing total cholesterol and "bad cholesterol," as well as decreasing triglycerides. By itself, Zetia has little effect on "good cholesterol"; and the drug is often used in combination with other cholesterol-lowering medications such as statins and fenofibrate. There are currently no known off-label uses.
Zetia® (ezetimibe) is a prescription medication that has been licensed to treat several conditions. These uses for Zetia include treating:
- High cholesterol (hypercholesterolemia), taken either alone or in combination with other cholesterol medications
- A rare genetic condition called sitosterolemia.
Zetia is used for treating high cholesterol in people who cannot lower their cholesterol through lifestyle changes alone. It can lower total cholesterol and LDL ("bad cholesterol") but has little effect on HDL ("good cholesterol"). The medication is often used in combination with other cholesterol-lowering drugs such as statins (Lipitor®, Crestor®, Zocor®, Pravachol®, Lescol®, Mevacor®) or fenofibrate (Antara®, Tricor®, Lipofen®, Triglide®, Lofibra®).