Cholesterol Home > Zetia Precautions and Warnings
Some warnings and precautions to be aware of with Zetia include:
- There are certain other medications that Zetia can interact with (see Zetia Drug Interactions).
- Cholesterol-reducing medications have been known to cause an increase in liver enzymes. This is especially true of statins (certain cholesterol medications often combined with Zetia). Your healthcare provider may check your liver function using a simple blood test to measure your liver enzymes, especially if you take Zetia with a statin.
- In very rare cases, people taking Zetia may develop serious problems in their muscles. These problems can lead to life-threatening complications. Therefore, make sure to contact your healthcare provider immediately if you experience any muscle pain, weakness, or tenderness, especially if it is accompanied by a fever or feeling of illness (see Zetia and Muscle Pain).
- Zetia is a pregnancy Category C medicine. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Zetia and Pregnancy).
- It is not known whether Zetia is excreted in breast milk. If you are breastfeeding and taking this drug, talk with your healthcare provider about whether you should continue the medicine (see Zetia and Breastfeeding).
You should not take Zetia if:
- You are allergic to Zetia or any component of Zetia or ezetimibe. Your healthcare provider or pharmacist has a list of the inactive ingredients.
- You have active liver disease or unexplained high liver enzymes.
- Are pregnant or breastfeeding (this applies only to taking those who take Zetia with a statin medication).