Lovaza is a prescription fish oil medication used for treating very high triglycerides. It contains two different omega-3 fatty acids (EPA and DHA) that work by decreasing the liver's production of triglycerides. Lovaza comes in capsule form and is taken once or twice a day. While most people tolerate this drug well, potential side effects include indigestion or heartburn, infections, and burping.
In studies, people with very high triglycerides who took Lovaza lowered their triglyceride levels by 44.9 percent, while people who took a placebo (a "sugar pill" with no active ingredients) actually increased their triglycerides by 6.7 percent. Other studies have shown that Lovaza is also effective for lowering triglycerides in people who are already taking statincholesterol medications.
Studies have shown that Lovaza can sometimes increase LDL cholesterol ("bad cholesterol"), so it is important for your healthcare provider to check your cholesterol levels regularly.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Lovaza [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2012 August.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed April 28, 2014.
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