Cholesterol Home > Lopid Side Effects

For the most part, side effects of Lopid are minor and easily treated. Some common side effects include heartburn or indigestion and nausea or vomiting. While you should tell your healthcare provider about any problems you experience while taking the drug, there are some reactions that require immediate attention. One serious side effect sometimes seen in people taking Lopid is rhabdomyolysis (serious breakdown of muscle).

Lopid Side Effects: An Introduction

As with any medicine, side effects are possible with Lopid® (gemfibrozil); but not everyone who takes the drug will have problems. In fact, most people tolerate it well. If side effects do occur, in most cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
The use of Lopid has been associated with a rare but serious side effect known as rhabdomyolysis (serious breakdown of muscle). Contact your healthcare provider immediately if you experience any unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or unusual tiredness (see Lopid and Muscle Pain).
(The article discusses most, but not all, side effects of Lopid. Your healthcare provider can discuss a more complete list of Lopid side effects with you.)

Common Side Effects of Lopid

Lopid has been studied thoroughly in clinical trials. In these studies, side effects are always documented and compared to those that occur in a similar group of people not taking the medicine. This way, it is possible to see what problems occurred, how often they occurred, and how they compared to the group not taking the medicine.
Based on these studies, the most common Lopid side effects include:
  • Heartburn or indigestion -- up to 19.6 percent
  • Abdominal pain (stomach pain) -- up to 9.8 percent
  • Diarrhea -- up to 7.8 percent
  • Fatigue -- up to 3.8 percent
  • Nausea or vomiting -- up to 2.5 percent.
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Last reviewed by: Kristi Monson, PharmD;
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