Cholesterol Home > Juvisync Warnings and Precautions

Your healthcare provider needs to know if you have a history of liver disease, pancreatitis, or kidney disease before you can start treatment with Juvisync. Other precautions for safely using this medicine include warnings of potential allergic reactions and drug interactions. This medicine can also cause other complications, such as pancreatitis and a potentially life-threatening breakdown of muscles.

In September 2013, Merck & Co, Inc., announced that it would be discontinuing this medication. It is clear that this decision was made for business reasons, not for safety reasons.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Juvisync® (sitagliptin/simvastatin) if you have:
  • A history of pancreatitis
  • Liver disease, liver failure, or a history of liver disease
  • Kidney disease or kidney failure
  • Hypothyroidism
  • Any allergies, including to foods, dyes, or preservatives.
Let your healthcare provider know if you are:
  • Pregnant or thinking about becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Also, make sure to contact your healthcare provider immediately if you experience any muscle pain, weakness, or tenderness, especially if it is accompanied by body aches or a fever.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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