The manufacturer of Juvisync (sitagliptin/simvastatin) recommends that women not use this drug while nursing, as it is unknown whether the medicine passes through human breast milk or if it would harm a nursing infant. Because this drug could affect blood sugar and cholesterol levels in a nursing infant, women should not use Juvisync while breastfeeding without first talking to their doctor.
In September 2013, Merck & Co, Inc., announced that it would be discontinuing this medication. It is clear that this decision was made for business reasons, not for safety reasons.
Can Breastfeeding Women Take Juvisync?
It is unknown if Juvisync® (sitagliptin/simvastatin) is safe for use while nursing. Currently, it is recommended that women should not take this product while breastfeeding. Therefore, you should talk with your healthcare provider before taking this medicine if you are breastfeeding or plan to start.
More Information on Juvisync and Breastfeeding
It is not known whether either of the active ingredients in Juvisync (simvastatin and sitagliptin) passes through breast milk in humans. It is also unclear whether Juvisync would cause significant problems in a nursing infant.
Because of the way it works, Juvisync might affect blood sugar levels and cholesterol levels in a breastfeeding infant, potentially causing serious problems. If the drug does happen to pass through breast milk, it is also thought that an infant would likely develop any of the possible Juvisync side effects.
Talking With Your Healthcare Provider
You should discuss breastfeeding and Juvisync use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Merck & Co., Inc. Merck provides update on combination medicine JUVISYNC (sitagliptin and simvastatin) tablets (September 26, 2013). Merck Web site. Available at: http://www.mercknewsroom.com/news/company-statements/merck-provides-update-combination-medicine-juvisync-sitagliptin-and-simvasta. Accessed October 25, 2013.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed October 20, 2011.
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