Because no human studies have been done on Caduet and breastfeeding, it's unclear if the medication passes through breast milk. The atorvastatin component passes through breast milk in rats, but it is unknown if the amlodipine component does. If Caduet does pass through breast milk, the risk to the nursing child is likely great, so if you are taking Caduet and breastfeeding is something you are considering, talk to your healthcare provider.
Caduet and Breastfeeding: An Overview
It is unknown if Caduet® (amlodipine and atorvastatin) passes through breast milk. Consequently, it is also not known if the drug is safe for women who are breastfeeding.
Caduet and Breastfeeding: What Does the Research Say?
Caduet is a combination drug, containing atorvastatin (Lipitor®) and amlodipine (Norvasc®). No research has been done to see if amlodipine passes through breast milk. Atorvastatin passes through breast milk in rats, but it is not known if the same is true for humans. In general, Caduet is not recommended for use in breastfeeding women.
You may be wondering why no studies have been done to see if Caduet passes through breast milk in humans. In many situations, such studies would be considered unethical. Such studies might put infants (who cannot themselves consent to these studies) at risk. In general, most information about breastfeeding and medications is obtained through cases outside of formal clinical studies.
Talking With Your Healthcare Provider About Caduet and Breastfeeding
You should talk with your healthcare provider about Caduet and breastfeeding. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, you and your healthcare provider can make a shared decision about Caduet and breastfeeding that is right for you.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Caduet [package insert]. New York, NY: Pfizer Inc;2013 November.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed August 13, 2007.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click