Lovaza and Pregnancy
In animal studies on Lovaza (omega-3-acid ethyl esters) and pregnancy, the medication decreased the number of live births and reduced the survival of newborn rats when it was given in high doses to pregnant rats. If you are taking Lovaza and pregnancy occurs, your healthcare provider will weigh the benefits and possible risks before making a recommendation for your situation.
Lovaza® (omega-3-acid ethyl esters) is a prescription omega-3 fish oil medication approved to treat very high triglycerides. At this time, it is not clear if Lovaza is safe for use during pregnancy.
The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating. A pregnancy Category C medicine may be given to pregnant women if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.
In animal studies, extremely high doses of Lovaza given to pregnant rats decreased the number of live births and decreased the survival of the newborn rats. However, this was not seen with lower doses (which were still much higher than the equivalent recommended dose for humans). Studies in pregnant rabbits did not cause any problems.
It is important to note that Lovaza is a very pure medication, made using a five-step refinement process. Pregnant women should not worry about mercury or other contaminants that can be found in other forms of fish oil.