Precautions and Warnings of Lovastatin

Specific Precautions and Warnings of Lovastatin

Precautions and warnings to be aware of prior to taking lovastatin include the following:
  • Lovastatin may interact with a number of other medications (see Drug Interactions With Lovastatin).
  • If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting lovastatin. Alcohol can affect the way the liver works, indirectly affecting lovastatin.
  • Statins have been known to cause an increase in liver enzymes, which can occasionally be a sign of liver damage. Therefore, it is recommended that you have a blood test that looks at your liver function before starting lovastatin and several months after treatment has started. These tests may also be recommended if the dosage is changed (see Mevacor and Liver Problems).
  • Rhabdomyolysis (the severe breakdown of muscles) and other serious muscle problems have rarely been reported with lovastatin and other statins. Make sure to contact your healthcare provider immediately if you experience any muscle pain, weakness, or tenderness, especially if it is with a fever or if you feel ill (see Mevacor and Muscle Pain for more information).
  • Studies suggest that lovastatin may be less effective (and more likely to cause side effects) in people with a genetic condition known as homozygous familial hypercholesterolemia.
  • Lovastatin is a pregnancy Category X medicine, meaning that it could potentially harm your unborn child. The safety of this drug in pregnant women has not been established. If you are pregnant, talk to your healthcare provider (see Mevacor and Pregnancy).
  • It is not known if lovastatin passes through breast milk. Therefore, ask your healthcare provider if you should stop nursing or discontinue the medication.
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