How Does It Work?

Lopid is part of a class of drugs known as the fibric acid derivatives. It is believed to work by slowing down the production of triglycerides and VLDL made in the liver. Lopid also causes an increase in HDL cholesterol. Depending on the type of cholesterol problem you have, Lopid may decrease LDL and total cholesterol levels.


Since Lopid can lower both cholesterol and triglyceride levels while raising HDL, a person can decrease his or her risk of developing certain health problems in the future.
In previous clinical research studies, people taking Lopid 900-1600 mg daily were able to:
  • Reduce triglycerides by 20 to 50 percent
  • Raise HDL cholesterol by 10 to 35 percent
  • Reduce LDL cholesterol by 5 to 20 percent.*
*In studies where people had triglyceride levels greater than 400 mg/dL, Lopid actually raised LDL levels.
Studies have also shown that people taking Lopid can significantly reduce their risk of coronary heart disease and sudden cardiac death (heart attack).

When and How to Take Lopid

Some general considerations for when and how to take the medication include:
  • It comes in tablet form and is taken by mouth twice a day. You are recommended to take it with a glass of water 30 minutes before morning and evening meals.
  • If upset stomach occurs, your dosage can be taken with milk or a light snack.
  • Lopid should be taken at the same time every day to help maintain an even level of the drug in the blood. Do not take it more often than directed.
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.
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Lopid Information

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