HMG-CoA Reductase Inhibitors (Statins)
The use of
Lopid with a statin medication should generally be avoided due to the increased risk of kidney and muscle problems. This combination should be used only if the benefit of further
lowering cholesterol levels outweighs the risk.
Repaglinide (Prandin)
Lopid can cause an increase in the levels of
repaglinide found in the blood. Repaglinide is a medication used to treat
diabetes, and high levels are associated with severe, prolonged hypoglycemia (low blood sugar). Therefore, this combination should generally be avoided.
Bexarotene (Targretin)
Lopid can cause an increase in the levels of bexarotene found in the blood. Bexarotene is an anti-cancer medication and some common side effects include elevated
cholesterol and
triglyceride levels. Therefore, this combination is not recommended.
Ezetimibe (Zetia)
The use of Lopid with
ezetimibe is not recommended due to a lack of clinical studies on this drug combination. The combination of these two medications may increase a person's risk of developing gallstones.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Cyclosporine can make it harder for Lopid to be eliminated from the body. If you are taking both Lopid and cyclosporine, you may be at increased risk of developing kidney problems (especially if you have kidney disease). Your healthcare provider may choose to monitor your progress more closely and make any necessary dosing adjustments.
Lopid Drug Interactions: Summary
It is possible that not every potential Lopid drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or doctor about the possible drug interactions with Lopid that may apply to you.