Fenofibrate is commonly prescribed to treat high cholesterol and high triglycerides. The medication is a form of fibrate and works by increasing the production of an enzyme that is responsible for breaking down triglyceride-rich particles and increasing their removal from the body. Fenofibrate comes in either capsule or tablet form -- your healthcare provider will tell you when and how to take it.
Fenofibrate is a prescription medication that is used to decrease triglycerides (a fat-like substance) and cholesterol levels in the body. It is sold under several different brand names, including:
Fenofibrate has been licensed for several uses, including:
- Improving cholesterol levels in people with hypercholesterolemia (high cholesterol) or dyslipidemia (unhealthy cholesterol levels). Fenofibrate can reduce total cholesterol, LDL ("bad" cholesterol), apo B (a component of cholesterol that is related to several heart disease risk factors), and VLDL (very low density lipoprotein cholesterol). The medication can also raise HDL ("good" cholesterol).
- Triglycerides in people with hypertriglyceridemia (high triglyceride levels). Very high triglyceride levels in the body increase the risk for developing a condition known as pancreatitis (inflammation of the pancreas).
Fenofibrate can actually cause an increase in LDL cholesterol for people with very high levels of triglycerides (greater than 350 mg/dL). Therefore, the medication should be used with extreme caution or not at all for people with this condition who also have high levels of LDL cholesterol.