Drug Interactions With Fenofibrate

When certain medicines are combined, there is a possibility of developing negative drug interactions. With fenofibrate, these interactions can lead to decreased absorption of the medicine and increased risks for kidney or muscle problems. Drugs that can interact with fenofibrate include warfarin, statins, and bile acid sequestrants. If drug interactions with fenofibrate are a concern, your healthcare provider may adjust your dosages or monitor you more closely.

 

Drug Interactions with Fenofibrate: An Introduction

Fenofibrate (Triglide™, Tricor®, Antara™, or Lofibra®) has the potential to interact with a number of other medications. Some of these drug interactions with fenofibrate include:
 
  • Warfarin (Coumadin®, Jantoven®)
     
  • HMG-CoA reductase inhibitors (statins), including:
  • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
     
  • Bile acid sequestrants (resins), including:
o Cholestyramine (Prevalite®, Questran®, Questran Light®, LoCholest®)

More Information on Interactions With Fenofibrate

The following sections provide more detailed information on how specific drugs interact with fenofibrate.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;