Crestor Drug Interactions

Red Yeast Rice
Red yeast rice is a supplement used to lower cholesterol. Taking it with Crestor may increase your risk of serious muscle problems, such as myopathy or rhabdomyolysis (see Crestor and Muscle Pain). In general, you should not use Crestor with red yeast rice.
 
Spironolactone
Theoretically, Crestor may decrease the level of steroid hormones in the body. Since spironolactone can also lower these hormone levels, taking these medications together may increase your risk of related problems. Talk to your healthcare provider before combining spironolactone with Crestor.
 
Warfarin
Taking Crestor and warfarin together may increase your risk of bleeding. When starting Crestor therapy or changing your Crestor dosing, your healthcare provider may choose to monitor your INR (the results of a blood-clotting test) more closely and make any necessary adjustments.
 

Final Thoughts on Crestor Drug Interactions

It is possible that not every drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific Crestor drug interactions that may apply to you.
 
Also, because a number of these medicines can increase the risk of serious muscle problems, if you have any unexplained muscle pain or weakness (especially if you have a fever or feel ill), contact your healthcare provider immediately.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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