Crestor Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Crestor is combined with any of the drugs listed above.
Antacids
If you are using
antacids while taking Crestor, make sure to take the antacid at least two hours after Crestor. Antacids may decrease the absorption of Crestor into your system, perhaps making it less effective.
Birth Control Pills
Taking
birth control pills with Crestor can increase the level of the hormones in the birth control pills, perhaps increasing your risk of side effects. Be sure to discuss this with your healthcare provider if you are currently using birth control pills.
Cimetidine
Theoretically, Crestor may decrease the level of steroid hormones in the body. Since
cimetidine can also lower these hormone levels, taking these medications together may increase your risk of related problems. Talk to your healthcare provider before combining cimetidine with Crestor.
Cyclosporine
Taking cyclosporine and Crestor simultaneously may greatly increase the level of Crestor in your blood. This can increase your risk of
Crestor side effects, including serious muscle problems, such as myopathy or rhabdomyolysis
(see Crestor and Muscle Pain). Your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments.
Fibrates
Taking a fibrate and Crestor at the same time may increase the level of Crestor in your blood. This can increase your risk of Crestor side effects, including serious muscle problems, such as myopathy or rhabdomyolysis
(see Crestor and Muscle Pain). In general, Crestor should not be taken with a fibrate. However, if your healthcare provider recommends taking these medications together, the maximum recommended dose of Crestor is lower than usual (10 mg per day).
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