If you develop any side effects while taking Crestor, or if your cholesterol levels do not improve, alternatives to this medication are available. Your healthcare provider may recommend other statins or an entirely different class of cholesterol medication. Some of these alternatives to Crestor include fibrates, nicotinic acid, bile acid sequestrants, and cholesterol absorption inhibitors.
Crestor® (rosuvastatin calcium) is a prescription cholesterol medication. For most people, it is quite effective at lowering cholesterol and is generally well tolerated. However, people may wish to consider a substitute for Crestor in some situations (such as if bothersome or dangerous side effects occur). Crestor alternatives might include other statins or other cholesterol medicines.
Keep in mind that lifestyle changes are the first line of treatment for lowering cholesterol. However, for some people, treating high cholesterol with diet, weight control, and exercise is not enough.
Crestor is part of a class of drugs called statins (or HMG-CoA reductase inhibitors). Statins work by blocking a particular enzyme, HMG-CoA reductase, that controls the rate of cholesterol production in the body. This causes the liver to make less cholesterol. Statins:
- Increase the liver's ability to collect and get rid of LDL cholesterol ("bad cholesterol")
- Increase HDL cholesterol ("good cholesterol")
- Decrease triglycerides.
Several statin medications are available that could be considered a substitute for Crestor. These include:
- Atorvastatin (Lipitor®) or combination medications that contain atorvastatin (Caduet®, Liptruzet™)
- Fluvastatin (Lescol®, Lescol® XL)
- Lovastatin (Altoprev®, Mevacor®) or combination medications that contain lovastatin (Advicor®)
- Pitavastatin (Livalo®)
- Pravastatin (Pravachol®)
- Simvastatin (Zocor®) or combination medications that contain simvastatin (Juvisync®, Simcor®, Vytorin®).