The dose of Cholestyramine that your healthcare provider recommends will vary, depending on a number of factors, including:
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As with any drug, do not adjust your Cholestyramine dosage unless your healthcare provider specifically instructs you to do so.
(Click Dosing With Cholestyramine for more information.)

Drug Interactions

There are several medications that may potentially interact with Cholestyramine (see Drug Interactions With Cholestyramine).


Treatment to lower cholesterol typically begins with lifestyle modifications. This includes a diet low in cholesterol (see Low Cholesterol Diet) and saturated fats, limited alcohol use, weight loss, and exercise. If lifestyle changes alone do not lower cholesterol levels to a desirable level, certain medications, such as Cholestyramine, may be necessary.
In general, cholesterol treatment is aimed at lowering LDL cholesterol levels enough to reduce the risk of developing complications associated with high cholesterol (see Effects of High Cholesterol). If you are at a higher risk, you will have a lower LDL goal.
(Click High Cholesterol Risk to see a list of risk factors that may affect your cholesterol level and a general guideline of ideal LDL cholesterol levels.)
For most people, Cholestyramine is quite effective in lowering cholesterol. It is also generally well tolerated. However, side effects can occur, and people may wish to consider a substitute for Cholestyramine. These substitutes could include other bile acid sequestrants, statins, or other cholesterol medicines.
(Click Cholestyramine Alternatives to learn more.)
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Cholestyramine Medicine

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