Cyclosporine
Taking
cyclosporine and
Caduet simultaneously may increase your risk of side effects due to the
atorvastatin (
Lipitor) component, including serious muscle problems, such as myopathy or rhabdomyolysis. Depending on your individual situation, your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments.
Digoxin
Caduet can increase the level of
digoxin in your blood, perhaps increasing your risk of
digoxin side effects. Your healthcare provider should monitor the level of digoxin in your blood and adjust your dose of this medication as necessary.
Diltiazem
Combining
diltiazem with Caduet may increase the level of Caduet in your blood, increasing your risk of side effects. Check with your healthcare provider before taking these medications together.
Efavirenz
Efavirenz may decrease the level of atorvastatin (one of the components of Caduet) in your blood. Check with your healthcare provider before taking Caduet and efavirenz together.
Fibrates
Taking a fibrate and Caduet at the same time may increase your risk of atorvastatin (Lipitor) side effects, including serious muscle problems, such as myopathy or rhabdomyolysis. Talk with your healthcare provider before combining these two medications.
Grapefruit Juice
Grapefruit juice can increase the level of the atorvastatin (Lipitor) component of Caduet
(see Lipitor and Grapefruit). In general, it is a good idea to avoid grapefruit juice while you are taking the drug.
Niacin
Combining
niacin with Caduet can increase the risk of serious muscle problems (such as myopathy or rhabdomyolysis) due to the atorvastatin (Lipitor) component of the drug. Talk with your healthcare provider before taking Caduet with niacin, including non-prescription niacin supplements.