High levels of triglycerides (fat-like substances) in the blood can have many negative effects on the body. They can accumulate on the walls of arteries, which decreases the blood flow and oxygen supply to the heart, brain, and other parts of your body. Hypertriglyceridemia can also increase a person's risk for developing heart disease, angina, a heart attack, and stroke.
Very high levels of triglycerides can produce a condition known as pancreatitis (inflammation of the pancreas). Pancreatitis can be quite painful and sometimes causes serious health problems.
Antara has been licensed for the treatment of high triglycerides in addition to diet and exercise. It works by increasing the breakdown and removal of these fat-like substances so there are less in the body.
Antara can actually cause an increase in LDL cholesterol for people with very high levels of triglycerides (greater than 350 mg/dL). Therefore, Antara should be used with extreme caution or not at all in people with this condition who also have high levels of LDL cholesterol.
Lowering triglyceride and cholesterol levels often begins with lifestyle modifications. This includes a diet low in cholesterol and saturated fats, limited alcohol use, weight loss, and exercise. If lifestyle changes alone do not lower triglyceride or cholesterol levels enough, certain medications, such as Antara, may be necessary.
Since Antara can lower both LDL cholesterol and triglyceride levels (along with lowering total cholesterol and increasing HDL), a person can decrease his or her risk of developing certain health problems in the future.
Antara has not been approved for use in children.