Niacin (Nicotinic Acid, Niacor, Nicolar)
Both
niacin and
Altoprev alone can increase the chances for developing serious muscle problems. Therefore, it is thought that combining these medicines may cause an even greater risk. If you are taking both Altoprev and niacin, your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments. The dose of Altoprev should not exceed 20 mg/day.
Antifungals (Ketoconazole [Nizoral], Fluconazole [Diflucan], Itraconazole [Sporanox])
There is a possibility that, when taking Altoprev with these medications, you are at higher risk of developing muscle problems. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.
Erythromycin, Clarithromycin, or Telithromycin
If you are taking Altoprev at the same time as you are taking
erythromycin,
clarithromycin, or telithromycin, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.
HIV Protease Inhibitors
If you are taking Altoprev at the same time as you are taking an
HIV protease inhibitor, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.
Examples of HIV protease inhibitors include:
Nefazodone (Serzone)
If you are taking both Altoprev and
nefazodone, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Unless your healthcare provider feels that the benefits outweigh the risks, these medicines should not be taken together.