Clinical Effects

In research studies, people taking Advicor 1000 mg/20 mg once in the evening were able to, on average, decrease LDL cholesterol by 30 percent, decrease triglycerides by 32 percent, and increase HDL by 20 percent. Generally, the effects on cholesterol and triglyceride levels were greater with higher doses of Advicor.

When and How Should I Take Advicor?

Some general considerations for when and how to take this medication include the following:
  • Your Advicor dosage should be taken at bedtime with a low-fat snack.
  • Swallow the tablet whole with a glass of water. Do not break, chew, or crush the tablets.
  • Alcohol, hot drinks, and spicy food may worsen flushing symptoms and itchy skin, which are common side effects of Advicor, and should therefore be avoided close to the time that the medicine is taken.


  • If you also take aspirin (which may help reduce flushing from Advicor), take your aspirin dose up to 30 minutes before taking Advicor. 


  • For Advicor to work properly, you have to take it as prescribed. The medication will not work if you stop taking it.

Dietary Instructions

People who are on Advicor should not drink grapefruit juice because it can increase the levels of medication in the blood, which can increase the risk of developing serious muscle problems. If you are being treated with Advicor and want to continue drinking grapefruit juice, talk to your doctor about other cholesterol-lowering medications that you can take.
(Click Grapefruit and Advicor for more information.)
As with any cholesterol medication, you should continue to eat a low fat, low cholesterol diet as part of your program to lower cholesterol.
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Advicor Medicine

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