Advicor Drug Interactions

More Information on Interactions With Advicor

The following sections explain in detail the potentially negative interactions that can occur when Advicor is combined with any of the drugs listed above.
 
Amiodarone
Taking both amiodarone and Advicor increases the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments.
 
Bile Acid Sequestrants
Bile acid sequestrants bind to niacin (one of the active ingredients of Advicor) in the digestive tract, preventing it from being absorbed into the bloodstream. This makes Advicor much less effective. Be sure to separate Advicor and a bile acid sequestrant by as much time as possible, at least four to six hours.
 
Blood Pressure Medications
Combining Advicor with a high blood pressure medication may increase the risk of low blood pressure (hypotension). Be sure to let your healthcare provider know if you develop any signs of this problem, such as lightheadedness, dizziness, or fainting. Check with your healthcare provider before taking these medications together, especially if you have recently had a heart attack or if you have unstable angina (a certain type of chest pain).
 
Certain Antibiotics
Some antibiotics may increase the level of Advicor in your blood, increasing the risk of side effects, including dangerous Advicor side effects such as myopathy or rhabdomyolysis. These medications should not be taken with Advicor; instead, alternative antibiotics should be recommended. If no suitable alternatives are available, you should stop taking Advicor while taking the antibiotic.
 
Certain Antifungals
Some antifungal medications may increase the level of Advicor in your blood, increasing the risk of side effects, including dangerous side effects such as myopathy or rhabdomyolysis. These medications should not be taken with Advicor; instead, an alternative antifungal should be recommended. If no suitable alternatives are available, you should stop taking Advicor while taking the antifungal.
(Advicor Drug Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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