Advicor Drug Interactions
More Information on Interactions With AdvicorThe following sections explain in detail the potentially negative interactions that can occur when Advicor is combined with any of the drugs listed above.
Taking both amiodarone and Advicor increases the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. If you take these medications together, the lovastatin component of your Advicor dose should not exceed 40 mg a day.
Bile Acid Sequestrants
Bile acid sequestrants bind to niacin (one of the active ingredients of Advicor) in the digestive tract, preventing it from being absorbed into the bloodstream. This makes Advicor much less effective. Be sure to separate Advicor and a bile acid sequestrant by as much time as possible, at least four to six hours.
Blood Pressure Medications
Combining Advicor with a high blood pressure medication may increase the risk of low blood pressure (hypotension). Be sure to let your healthcare provider know if you develop any signs of this problem, such as lightheadedness, dizziness, or fainting. Check with your healthcare provider before taking these medications together, especially if you have recently had a heart attack or if you have unstable angina (a certain type of chest pain).
Boceprevir can increase blood levels of Advicor, thereby increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Because of this risk, these medications should not be used together.
Some antibiotics may increase the level of Advicor in your blood, increasing the risk of side effects, including dangerous Advicor side effects such as myopathy or rhabdomyolysis. These medications should not be taken with Advicor; instead, alternative antibiotics should be recommended. If no suitable alternatives are available, you should stop taking Advicor while taking the antibiotic.